Which assessment findings would indicate to the nurse that a patient receiving vincristine is experiencing a toxic reaction? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply
1. The patient reports being too weak to get out of bed much of last week.
2. The patient has lost her hair.
3. The patient reports constipation.
4. The patient reports that she cannot feel her feet.
5. The patient has a high fever and shaking chills this morning.
1,4,5
Rationale 1: Neurologic changes such as motor weakness are a sign of toxicity.
Rationale 2: Alopecia is an expected effect of this regimen. The nurse should provide information about the use of wigs, hats, or caps.
Rationale 3: Constipation is a common effect of this regimen. The nurse should provide information about laxatives and stool softeners.
Rationale 4: Paresthesias are an effect of toxicity.
Rationale 5: A high fever and shaking chills indicate infection, which may be related to toxicity from this regimen.
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