A female patient who begins taking spironolactone [Aldactone] as an adjunct to furosemide [Lasix] complains that her voice is deepening. What will the nurse do?
a. Contact the provider to obtain an order for a complete blood count (CBC) and liver function tests.
b. Explain that this drug binds with receptors for steroid hormones, causing this effect.
c. Report this side effect to the provider and request another medication for this pa-tient.
d. Teach the patient to report any associated cough, which may indicate a more severe side effect.
B
Spironolactone binds with receptors for aldosterone and with other steroid hormones, causing side effects such as gynecomastia, menstrual irregularities, impotence, hirsutism, and deepening of the voice. There is no indication for a CBC or for liver function tests in this patient with this side effect. Deepening of the voice is not an indication for withdrawal of the drug. This side ef-fect is not associated with cough.
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