The tumor of a patient being treated with cisplatin and topotecan becomes partially resistant by overexpressing glutathione S-transferase. If you don't want to replace a drug with another drug that has similar MOA, and you don't want the two resulting drugs to have similar MOA either, then which of the following changes would represent the best recommendation?
A. Discontinue topotecan and add dacarbazine
B. Discontinue topotecan and add doxorubicin
C. Discontinue cisplatin and add cyclophosphamide
D. Discontinue cisplatin and add taxol
E. Discontinue cisplatin and add irinotecan
Answer: D. Discontinue cisplatin and add taxol
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The nurse is monitoring a pregnant woman who is at high risk for the development of disseminated intravascular coagulation (DIC). What physical assessment findings would indicate of DIC?
A) Urine clear without sediment at 40 mL/hr B) Oozing blood from all intravenous sites C) All vital signs within expected parameters for pregnancy D) Absence of elevated protein in urine or serum
A patient has arterial blood gas testing performed. His PaO2 is 83 mm Hg, SaO2 is 91%, pH is 7.5, PaCO2 is 24 mm Hg, and HCO3 is 22 mEq/L. Which of the following indicates this patient's condition?
A) Respiratory acidosis with normal saturation (uncompensated) B) Metabolic alkalosis with low saturation (uncompensated) C) Respiratory alkalosis with low saturation (uncompensated) D) Metabolic alkalosis with low saturation (fully compensated)
The nurse is caring for an older adult patient who presented to the emergency department with delirium. For which conditions will the nurse assess the patient? Select all that apply
1. Drug abuse 2. Infection 3. Drug toxicity 4. Hypoxemia 5. Fluid volume deficit
The nurse is preparing to perform an interview to obtain information about the client. Which of the following are classified as secondary sources of information? Standard Text: Select all that apply
1. The client's wife 2. The client's medical record from his last hospital admission 3. The client 4. The client's daughter 5. The client's physical therapist