When conducting a review of a proposal, which of the following questions would be concerns of an institutional review board (IRB)? (Select all that apply.)
a. Is this study congruent with our hospital's research agenda?
b. What will be the impact of this study on our hospital and its clients?
c. Is this proposal literate and well written?
d. Does this study have any scientific merit?
e. What prior research experience does this author have?
f. Will the human subjects studied be protected from harm?
g. What is the quality of this study?
ANS: A, B, D, F, G
Clinical agencies and health care corporations review studies for the following reasons: (1) to evaluate the quality of the study, (2) to ensure that adequate measures are being taken to protect human subjects, and (3) to evaluate the impact of the study on the reviewing institution. Most agency IRBs screen proposals for (1) scientific merit, (2) protection of human rights, (3) congruence of the study with the agency's research agenda, and (4) impact of the study on patient care.
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