Of the following aging theory examples, which one supports the nonstochastic beliefs about aging?

A)
Mitochondrial DNA damage has accumulated to such a level that the person has physiological symptoms of declining health.
B)
Oxidative free radicals result in by-products that react with DNA to lead to cellular damage.
C)
The wear-and-tear theory of aging states that accumulated damage to vital parts of cells leads to cellular aging and death.
D)
Mutations in BRCA1 and BRCA2 have been associated with increased risk for developing breast and ovarian cancer.


Ans:
D

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Nonstochastic theories focus on genetic influences that determine physical condition, occurrence of disease, age of death, cause of death, and other factors contributing to longevity. Many genes that are associated with the human life span are not "longevity genes," per se. For example, because mutations in the tumor suppressor genes BRCA1 and BRCA2 increase mortality rates associated with breast and ovarian cancer, they are rare among long-lived women. The mitochondrial DNA damage theory, oxidative free radical theory, and wear-and-tear theory are all stochastic theories of aging.

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