The nurse reviews a client's current medications and realizes that which medications would be contraindicated in testosterone replacement therapy?
Standard Text: Select all that apply.
1. Oral anticoagulants
2. Corticosteroids
3. Finasteride
4. Antibiotics
5. Antihypertensives
Correct Answer: 1,2,3
Rationale 1: Testosterone may potentiate the effects of oral anticoagulants and increase the risk of severe bleeding.
Rationale 2: Use of testosterone with corticosteroids may cause additional edema.
Rationale 3: Finasteride is an antiandrogenic medication; if used with testosterone, it inhibits the effects of both medications.
Rationale 4: Testosterone is not contraindicated with the use of antibiotics.
Rationale 5: Testosterone is not contraindicated with the use of antihypertensives.
Global Rationale: Testosterone may potentiate the effects of oral anticoagulants and increase the risk of severe bleeding. Use of testosterone with corticosteroids may cause additional edema. Finasteride is an antiandrogenic medication; if used with testosterone, it inhibits the effects of both medications. Testosterone is not contraindicated with the use of antibiotics or antihypertensives.
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