How does the Roux-en-Y procedure affect digestion and absorption? Do other surgical procedures discussed in question #5 have similar effects?
What will be an ideal response?
• Significant section of stomach bypassed, reducing gastric acid needed for promoting the ferrous state of iron (needed for absorption) and reduced intrinsic factor for B12 absorption
• Additionally, gastric acid is needed to cleave many minerals and vitamins from other molecular structures and promote their absorbable forms
• Duodenum and proximal jejunum bypassed, thus reducing the overall surface area and time for digestion and absorption
• Lactose intolerance may transiently occur due to the production of lactase in the removed part of the small intestine; adaptation can occur
• Deficiencies in fat-soluble vitamins (A, D, E, K), vitamin B12, folate, iron, and calcium are common
• Other surgical procedures like the duodenal switch and biliopancreatic diversion may have similar effects due to their alterations in the GI tract pathways/release of digestive enzymes
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