A nurse is discussing microbial resistance among sulfonamides and trimethoprim with a nursing student. Which statement by the student indicates a need for further teaching?
a. "Bacterial resistance to trimethoprim is relatively uncommon."
b. "Resistance among gonococci, streptococci, and meningococci to sulfonamides is high."
c. "Resistance to both agents can occur by spontaneous mutation of organisms."
d. "Resistance to sulfonamides is less than resistance to trimethoprim."
ANS: D
There is less microbial resistance to trimethoprim than there is to sulfonamides. Bacterial resistance to trimethoprim is relatively uncommon. Gonococcal, streptococcal, and meningococcal resistance to sulfonamides is especially high. For both agents, resistance can develop by spontaneous mutation.
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