Which of the following statements about screening for prostate cancer is most accurate?
A) Digital rectal examination detects the majority of new cases of prostate cancer.
B) A positive prostate-specific antigen (PSA) test is definitive for prostate cancer.
C) BPH and prostatitis can confound prostate screening results.
D) Digital rectal examination and PSA testing have been proven ineffective.
Ans: C
Feedback:
PSA is a glycoprotein secreted into the cytoplasm of benign and malignant prostatic cells that is not found in other normal tissues or tumors. However, a positive PSA test indicates only the possible presence of prostate cancer. It also can be positive in cases of BPH and prostatitis. Detection using digital rectal examination varies from 1.5% to 7%. Screening remains somewhat controversial, but it has not been proven wholly ineffective.
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