A client is beginning to take trimethoprim-sulfamethoxazole (Bactrim) for a recurrent urinary tract infection (UTI). The nurse would give the client which of the following instructions regarding this medication?
1. Discontinue medication when symptoms subside.
2. Expect rashes or skin changes as a result of therapy.
3. Take most doses early in the day when fluid intake is greatest.
4. Take each dose with 8 oz of water, and drink extra water each day.
4
Rationale: Bactrim is a combination medication, with both sulfamethoxazole and trimethoprim. The client takes each dose with 8 oz of water and drinks several extra glasses of water each day. The client should space doses evenly around the clock for stable blood levels and should take the medication for the full course of therapy. The client should report rashes or other skin changes, which could indicate an allergy to sulfa.
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