A patient with polycystic ovary syndrome (PCOS) asks the nurse what she can do to improve her chances of getting pregnant. Which statement by the patient indicates a need for further teaching?
a. "Clomiphene will help induce ovulation but will not treat the other symptoms of polycystic ovarian disease."
b. "If I lose weight, my infertility and irregular periods could resolve without medications."
c. "Metformin improves insulin sensitivity and reduces male hormone levels."
d. "Spironolactone, which reduces androgens and facial hair, is helpful if I'm trying to conceive."
ANS: D
Spironolactone is antiandrogenic; it can reduce hirsutism and acne, but it also can harm the fetus and should not be used in patients trying to conceive. Clomiphene helps induce ovulation but does not treat symptoms of PCOS. Patients who lose weight might experience a reversal of symptoms without medications, although weight loss may be difficult to achieve. Metformin reduces serum insulin levels by increasing insulin sensitivity and indirectly lowers androgen levels.
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