Using the example of the p53 protein, postulate how different combinations of covalent modifications can lead to a wide variety of protein functions

What will be an ideal response?


In a protein with a complex regulatory protein code, such as p53, the covalent attachment or removal of modifying groups can change the protein's behavior, its activity or stability, its binding partners, or its location within a cell. In the case of p53, there are at least 20 different locations (amino acids) that can be modified through such processes as phosphorylation, ubiquitylation, and acetylation.

Biology & Microbiology

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Due to the formation of an inversion loop, sections of DNA may either be duplicated or deleted depending on the size of the inversion

Indicate whether the statement is true or false

Biology & Microbiology

If you want to prevent a grass seedling shoot from bending toward light, you should ____

a. remove the shoot tip b. place a translucent cap on the shoot tip c. place an opaque cap on the shoot tip d. either remove the shoot tip or place a translucent cap on the shoot tip e. either remove the shoot tip or place an opaque cap on the shoot tip

Biology & Microbiology

Which of the following is mismatched?

A. Coxiella burnetti: cowpox B. Chlamydia trachomatis: blindness C. Rickettsia rickettsii: Rocky Mountain Spotted Fever D. Rickettsia typhi: endemic typhus E. All of these choices are correct.

Biology & Microbiology

Where are phospholipids most likely found in a prokaryotic cell?

A) flagella B) around organelles C) the plasma membrane D) ribosomes E) the plasma membrane and around organelles

Biology & Microbiology