A variety of smooth muscle relaxants can promote the occurrence of "Ca++ sparks" beneath sarcolemma of smooth muscle
The Ca++ sparks are thought to originate from a local activation of the ryanodine receptor, just beneath the sarcolemma. These Ca++ sparks promote relaxation by:
A. activating the Na+-Ca++ antiporter in the smooth muscle
B. activating the Ca++-dependent phosphatase calcineurin in the smooth muscle
C. activating Ca++-dependent K+ channels in the smooth muscle
D. promoting myosin light chain phosphorylation smooth muscle
E. activating Rho kinase in the smooth muscle
ANS: C
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