Rough endoplasmic reticulum (RER) in the cell cytoplasm is intensely stained by hematoxylin because hematoxylin:
a. Attaches to lipids in RER membranes
b. Binds readily to RNA
c. Catalyzes the precipitation of ribosomes into a dense, readily stained matrix
d. Is an acid dye and binds to acidophilic ribosomal proteins
e. Reacts with carbohydrate molecules of integral membrane proteins
ANS: B
The metal ions associated with hematoxylin impart a positive charge to the dye, which enables it to bind to negatively charged molecules like acids (e.g., ribonucleic acid). See 1-1.
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