A particular reaction has a negative delta G. However, this reaction takes many years to proceed in the absence of enzyme. Why is this the case?
A. This reaction does not obey the second law of thermodynamics.
B. A certain amount of activation energy is required for the reaction to proceed.
C. This reaction does not proceed spontaneously.
D. The initial free energy of the reactants is much less than the final free energy of the products.
Answer: B
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