A client being discharged with a prescription for penicillin also takes probenecid. The nurse explains that probenecid:
1. prevents diarrhea often associated with penicillin.
2. will prevent an allergic response.
3. is a secondary antibiotic.
4. will allow the penicillin to stay in the body longer.
Correct Answer: 4
Rationale 1: Probenecid will not treat diarrhea associated with penicillin.
Rationale 2: Probenecid is not an anti-inflammatory, and will not prevent allergic responses.
Rationale 3: Probenecid is not an antibiotic.
Rationale 4: Probenecid prevents the renal excretion of penicillin and allows it to remain in the system longer.
Global Rationale: Probenecid decreases excretion of penicillins and can lead to antibiotic toxicity. This is sometimes a desired effect but the patient will require monitoring.
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