A patient has been admitted to a medical unit with a diagnosis of polymyalgia rheumatica (PMR). The nurse should be aware of what aspects of PMR? Select all that apply
A) PMR has an association with the genetic marker HLA-DR4.
B) Immunoglobulin deposits occur in PMR.
C) PMR is considered to be a "wear-and-tear" disease.
D) Foods high in purines exacerbate the biochemical processes that occur in PMR.
E) PMR occurs predominately in Caucasians.
Ans: A, B, E
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The underlying mechanism involved with polymyalgia rheumatica is unknown. This disease occurs predominately in Caucasians and often in first-degree relatives. An association with the genetic marker HLA-DR4 suggests a familial predisposition. Immunoglobulin deposits in the walls of inflamed temporal arteries also suggest an autoimmune process. Purines are unrelated and it is not a result of physical degeneration.
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