A client admitted with iron deficiency anemia has clinical symptoms related to which abnormal laboratory value?
1. Low levels of iron-bound transferrin
2. High levels of iron-bound transferrin
3. High levels of ferritin
4. High hemoglobin level
Low levels of iron-bound transferrin
Rationale: Iron is required for the heme portion of the hemoglobin protein; it is coupled with the iron-transporting protein transferrin. Thus erythrocyte production is slowed when iron-dependent hemoglobin supplies are depleted or insufficient in contrast to high levels of ferritin, which may indicate other types of anemias—hemolytic, pernicious, and folic acid deficiency, liver damage, or thalassemia. Ferritin is an iron-storage protein that is produced in the liver, spleen, and bone marrow. High ferritin levels are related to the amount of iron stored in the body tissues, and would indicate disorders related to chronic diseases such as leukemia, lymphoma, iron overload, and tissue damage. A high hemoglobin level indicates hemoconcentration resulting from dehydration, which does not typically occur in iron deficiency anemia.
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