List the tests that are commonly utilized in the workup of the following:
a. von Willebrand's disease
b. Hemophilia A
c. Factor VIII inhibitor
d. Bernard-Soulier syndrome
e. TTP
What will be an ideal response?
Answer:
von Willebrand's disease: PT, APTT, BT, VWF:Ag, VWF activity (RIPA), platelet count, factor VIII, and VWF multimer analysis
Hemophilia A: PT, APTT, and factor VIII
Factor VIII inhibitor: factor VIII activity, Bethesda titer, and mixing study
Bernard-Soulier syndrome: BT, platelet aggregation studies, and platelet count
TTP: bleeding time, platelet aggregation studies, and platelet count
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