Insulin stimulates an increase in number of glucose carrier proteins at a cell membrane's surface. What effect will insulin have on cell function? Choose all that apply.A) An increase in insulin, which will increase the diffusion rate.B) ATP amounts needed for this transport will increase.C) Low insulin levels will decrease the number of available carrier proteins.D) Lack of membrane receptors for insulin will decrease amount of glucose taken in.
What will be an ideal response?
A, C, D
Clarify Question
• What is the key concept addressed by the question?
o The question asks about glucose transport.
• What type of thinking is required?
o You are being asked to analyze statements about glucose transport.
Gather Content
• What do you know about glucose transport? What other information is related to the question?
o Passive transport of glucose indicates that glucose is moving down its concentration gradient through the GLUT transporter. This means that it does not require ATP or cotransport of water. The GLUT transporter is a protein that makes a pore through the membrane of cells allowing glucose to enter. The number of glucose transporters on the surface of the cell is controlled in part by insulin. Insulin binds to receptors on the surface of the cell and causes more transporters to be present on the cell, increasing the rate of glucose diffusion into the cell.
Choose Answer
• Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?
o As insulin increases, more GLUT transporters appear on the surface of the cell, increasing the rate of glucose diffusion into the cell. If insulin levels or the number of insulin receptors drop there will be no increase in GLUT transporters on the surface of the cell and glucose uptake will decrease.
Reflect on Process
• Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
o This question asked you to analyze statements about glucose transport. If you got the correct answer, great job! If you got an incorrect answer, where did the process break down? Did you think that ATP was necessary for glucose diffusion into a cell? Did you think that the insulin receptor was not needed for glucose uptake?
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