Which is the best response made by the nurse providing education to a patient taking ketoconazole for a fungal infection?
a. "You may take this medication with an antacid."
b. "Alcohol has no effect on this medication."
c. "Take this medicine 2 hours after taking an H2 blocker.
d. "It is okay to skip a dose if you feel better."
ANS: C
Because antacids, anticholinergics, and H2 blockers (e.g., Pepcid, Zantac) change gastrointestinal (GI) pH, the patient should not take ketoconazole for at least 2 hours after taking any H2 blockers.
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