Which of the following characteristics describe a malignant tumor? (Select all that apply.)
a. The cells resemble the tissue of origin.
b. The cells can travel to distant organs and initiate new tumors.
c. The cells may invade surrounding tissues.
d. Tissue damage is minimal.
e. The growth rate is rapid.
ANS: B, C, E
Malignant cells tend to travel (metastasize) to distant sites, and their growth rate is often rapid. Normal cells resemble their tissue of origin; most cancers are not well differentiated. Cancer cells also lack contact inhibition, and so they invade surrounding tissue.
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