A male, lifetime smoker has died because of chronic obstructive pulmonary disease. Which of the following phenomena regarding his alveoli would his care team expect in the weeks prior to his death?
A)
Proliferation of natural killer (NK) cells in the alveolar lumen
B)
Large numbers of alveolar macrophages in septal connective tissue
C)
The presence of tubercles in the interalveolar spaces
D)
Compensatory regeneration of type I alveolar cells
Ans:
B
Feedback:
Smokers often retain large numbers of carbon-filled macrophages in their septal connective tissue. NK cell proliferation is not a noted phenomenon in the alveoli, and tubercles are associated specifically with tuberculosis infection. Type I alveoli are incapable of regeneration.
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