A microarray is a tool used in genetic research to determine the mRNAs being produced in a particular tissue, and their relative level of expression. Known genes can therefore be assayed for their expression in different situations
One use of the technology is in cancer diagnosis and treatment. If a known gene functions as a tumor suppressor, predict which of the following pieces of evidence would be most useful in diagnosis of a cancer due to a mutation in this tumor-suppressor gene. A) The tissue sample shows a high level of gene expression relative to a control (noncancerous) sample.
B) The tissue sample responds to treatment with a mitosis-promoting compound.
C) The mRNAs for the targeted tumor suppressor sequence are not being produced.
D) The mRNAs for cyclins and kinases show unusually high levels of expression.
C
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Stool received for routine culture in most clinical laboratories in the United States should be examined for the presence of at least:
a. Campylobacter, Salmonella, and Shigella spp. b. Salmonella and Shigella spp. c. Campylobacter and Vibrio spp. d. Salmonella, Shigella, and Vibrio spp.
If the K+ channels of an excitable plasma membrane were blocked by the action of a drug, which of the
following would be disrupted?
a. repolarization b. depolarization c. hyperpolarization d. repolarization and depolarization e. repolarization and hyperpolarization
Bacteriostatic agents kill bacterial cells.
Answer the following statement true (T) or false (F)
Individuals with the same genetic background and a high degree of homozygosity are said to be isogenic. Of what value are isogenic strains in genetic studies?
What will be an ideal response?