A premature infant is at greater risk for infection than a full-term infant because of a reduced number of which immunoglobulin?
1. IgE
2. IgG
3. IgA
4. IgM
2
Rationale 1: IgE does not cross the placenta and is not present at birth in either preterm or full-term infants.
Rationale 2: Maternal IgG crosses the placenta. Newborns' levels are similar to their mothers'. Premature infants have lower levels of IgG obtained from their mothers and are at greater risk for infection.
Rationale 3: IgA does not cross the placenta and is not present at birth in either preterm or full-term infants.
Rationale 4: IgM does not cross the placenta. The levels are low at birth in both preterm and full-term infants.
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