From the following list, which medications have been developed utilizing recombinant DNA technology? Select all that apply
A) Insulin, for clients with diabetes
B) Coumadin, a blood thinner for irregular heartbeats
C) Erythropoietin to help the body generate more RBCs
D) Tissue plasminogen activator (tPA) to dissolve a clot in the brain
E) Zyrtec, for allergies
Ans: A, C, D
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Recombinant DNA technology has also made it possible to produce proteins that have therapeutic properties. One of the first products to be produced was human insulin. More complex proteins are produced in mammalian cell culture using recombinant DNA techniques. These include erythropoietin, which is used to stimulate red blood cell production; factor VIII, which is used to treat hemophilia; and tissue plasminogen activator (tPA), which is frequently administered after a heart attack to dissolve the thrombi that are obstructing coronary blood flow. Coumadin and Zyrtec are not manufactured using recombinant DNA technology.
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