When a patient presents at the emergency department for an allergic reaction, the nurse recogniz-es the most severe consequence of a type I hypersensitivity reaction is:

a. urticaria.
b. hives.
c. anaphylaxis.
d. antibody-dependent cell-mediated cyto-toxicity (ADCC).


ANS: C
The most rapid and severe immediate hypersensitivity type I reaction is anaphylaxis. Urticaria, or hives, is a dermal (skin) manifestation of allergic reactions. Hives and urticaria are similar re-sponses. ADCC is a mechanism that involves natural killer (NK) cells. Antibodies on the target cell are recognized by Fc receptors on the NK cells, which release toxic substances that destroy the target cell.

Nursing

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