One of the important inherited defects in the second line of immune defense is a condition called chronic granulomatous disease. What is this disease, and how is it caused?

What will be an ideal response?


Chronic granulomatous disease is a type of primary immunodeficiency. It is an inherited condition seen in children who have recurrent infections, especially with bacteria. It is due to the inability of phagocytes to produce reactive forms of oxygen and therefore fail to kill ingested bacteria. A CBC would have normal levels of lymphocytes.
Bloom's Taxonomy: Application
Section: Immunodeficiency Diseases
Learning Outcome: 18.18

Biology & Microbiology

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Evidence of ________ supports the hypothesis that eukaryotes are derived from bacteria

A) antibiotic resistance B) DNA content in the nucleus C) ribosome contents D) ribosome contents and DNA content in the nucleus

Biology & Microbiology

All of the following are unique to plant cells except

A) leaf peroxisomes. B) glyoxysomes. C) nodule peroxisomes. D) peroxisomes. E) chloroplasts.

Biology & Microbiology

At the site of infection, leukocytes are stimulated to express ________, which causes them to attach to the endothelial cells before moving into the vessel wall.

A) integrins B) selectins C) chemotactic factor D) marginin E) attachins

Biology & Microbiology

P680+ is said to be the strongest biological oxidizing agent. Given its function, why is this necessary?

A) It is the receptor for the most excited electron in either photosystem of photosynthesis. B) It is the molecule that transfers electrons to plastoquinone (Pq) of the electron transfer system. C) It transfers its electrons to reduce NADP+ to NADPH. D) It obtains electrons from the oxygen atom in a water molecule, so it must have a stronger attraction for electrons than oxygen has.

Biology & Microbiology