What description identifies the pathophysiology of leukemia?
a. Increased blood viscosity
b. Abnormal stimulation of the first stage of coagulation process
c. Unrestricted proliferation of immature white blood cells (WBCs)
d. Thrombocytopenia from an excessive destruction of platelets
ANS: C
Leukemia is a group of malignant disorders of the bone marrow and lymphatic system. It is defined as an unrestricted proliferation of immature WBCs in the blood-forming tissues of the body. Increased blood viscosity may result secondary to the increased number of WBCs. The coagulation process is unaffected by leukemia. Thrombocytopenia may occur secondary to the overproduction of WBCs in the bone marrow.
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