When reading about a drug, the nurse learns it has a median toxic dose of 50 mg. The patient has been receiving 60 mg of the drug. What analysis does the nurse make?
1. It is likely the drug will not produce the desired effect.
2. The efficacy and potency of this drug have not been well defined.
3. The patient will be at greater risk of adverse effects.
4. This amount of drug would have been lethal to half the population.
3
Rationale 1: This information is insufficient to predict if the drug will produce the desired effect.
Rationale 2: The median toxicity dose is not a measure of efficacy and potency.
Rationale 3: Since the dose exceeds the median toxicity for this drug, the patient is at greater risk of developing adverse effects.
Rationale 4: Median toxicity dose has to do with development of toxicity, not lethality.
Global Rationale: Since the dose exceeds the median toxicity for this drug, the patient is at greater risk of developing adverse effects. This information is insufficient to predict if the drug will produce the desired effect. The median toxicity dose is not a measure of efficacy and potency. Median toxicity dose has to do with development of toxicity, not lethality.
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Which statement regarding construct validity of a measurement instrument is accurate?
1. It is established by complex statistical procedures. 2. It is used to determine that items on the tool adequately represent conceptual definitions of variables in the study. 3. It is concerned with the ability of an instrument to predict behavior of subjects in the future. 4. It is the measurement of a variable that is not directly observable.
Regina Smith is a 25-year-old primigravida in the first stage of labor. She and her husband have been holding hands and breathing together through each contraction
Suddenly Regina pushes her husband's hand away and shouts, "Don't touch me!" This behavior is most likely: a. normal and related to hyperventilation. b. common during the transition phase of labor. c. a sign that she needs analgesia. d. indicative of abnormal labor.
The charge nurse is concerned with reducing the stressors of hospitalization. Which nursing intervention is most helpful in decreasing the stressors for toddlers?
1. Assign the same nurse to the toddler as much as possible. 2. Let the child listen to an audiotape of the mother's voice. 3. Place a picture of the family at the bedside. 4. Encourage a parent to stay with the child.
During a physical examination of a 74-year-old patient, the nurse palpates the point of maximal impulse (PMI) in the sixth intercostal space lateral to the left midclavicular line. The most appro-priate action for the nurse to take next will be to
a. ask the patient about risk factors for ath-erosclerosis. b. document that the PMI is in the normal anatomic location. c. auscultate both the carotid arteries for the presence of a bruit. d. assess the patient for symptoms of left ventricular hypertrophy.