What key advantage do emerging technologies, such as MALDI-TOF and next generation sequencing, have over conventional hybridization and amplification techniques?
a. They do not require selection of suspected pathogens prior to testing.
b. They do not require expensive instrumen-tation or skilled technicians.
c. They eliminate sample preparation steps, such as nucleic acid purification, prior to testing.
d. They are readily available in most clinical laboratories.
e. All of the above.
A
MALDI-TOF and NGS allow examination of all proteins/nucleic acids within a sample and do not require identification of suspected pathogens as do hybridization/amplification techniques in order to select appropriate probe sequences.
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Answer the following statement true (T) or false (F)