The clinic nurse provides teaching for a patient prescribed pyrimethamine (Daraprim) to prevent malaria and instructs on the need to notify the prescriber immediately if what signs and symptoms occur?
A) Diarrhea, fatigue, weight loss, and anemia
B) Irritation, rash, or inflammation
C) Headache, nausea, or constipation
D) Anorexia, nausea, or vomiting
A
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If signs of folate deficiency develop, pyrimethamine will need to be discontinued so the prescriber needs to be notified immediately. Folate deficiency presents with diarrhea, fatigue, weight loss, and anemia. The other signs and symptoms would need to be reported if significant and/or long-lasting.
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