Explain why lactose intolerance is considered a variation in gene expression rather than a genetic disorder. What will be an ideal response?
ANSWER: Lactose intolerance is not considered a genetic disorder, but rather a variation in gene
expression because there is no faulty gene or metabolic pathway breakdown involved.
Lactose intolerance is due to wide phenotypic differences in the ability to digest lactose
resulting from various ‘normal’ allelic combinations. These allelic combinations do not
contain any ‘faulty’ genes that disrupt normal metabolism, but rather express themselves
‘normally,’ making some people lactose intolerant and others not.
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