A 49-year-old man died of complications of AIDS. At autopsy, the pathologist found numerous pulmonary infarcts. Histologically, the thrombi in the branches of the pulmonary artery were permeated with broad hyphae branching at an acute angle
These hyphae also extended into the vessel wall. This infection was most likely caused by
A. Aspergillus fumigatus
B. Candida albicans
C. Cryptococcus neoformans
D. Histoplasma capsulatum
E. Blastomyces dermatitidis
A
Aspergillus fumigatus is an opportunistic deep fungal infection that affects immunosuppressed persons. The hyphae of the fungi penetrate into the vessel wall, causing thrombi and infarcts. Other fungi listed here do not form branching hyphae and do not invade the vessel wall followed by thrombi.
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