What is the cause of type 1 diabetes mellitus (DM)?

a. A familial, autosomal dominant gene de-fect
b. Obesity and lack of exercise
c. Immune destruction of the pancreas
d. Hyperglycemia from eating too many sweets


ANS: C
The most common cause of type 1 DM is a slowly progressive autoimmune T-cell-mediated dis-ease that destroys the beta cells of the pancreas; it is not due to a gene defect. Although obesity can contribute to diabetes, it doesn't cause type 1 DM. Eating too many sweets may contribute to the development of obesity.

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