The nurse is preparing to administer a drug and learns that it binds to protein at a rate of 90%. The patient's serum albumin level is low. The nurse will observe the patient for
a. decreased drug absorption.
b. decreased drug interactions.
c. decreased drug toxicity.
d. increased drug effects.
ANS: D
Drugs that are highly protein-bound bind with albumin and other proteins, leaving less free drug in circulation. If a patient has a low albumin, the drug is not bound, and there is more free drug to cause drug effects. There would be increased absorption, increased interactions with other drugs, and increased toxicity.
You might also like to view...
Which of the following makes you expect elder abuse when Annie, aged 94, shows you cigarette burns on her upper arms and back? Annie states
A) "I burned myself when I fell asleep smoking." B) "I take my own medications at home." C) "I don't like being alone during the day." D) "Look at this mark here."
When teaching about hypoglycemia, the nurse will make sure that the patient is aware of the early signs of hypoglycemia, including:
a. hypothermia and seizures. b. nausea and diarrhea. c. confusion and sweating. d. fruity, acetone odor to the breath.
A nurse has seen several clients at a community health center. Which of the clients would be most at risk for developing an infection?
A) An older adult with several chronic illnesses B) An infant who has just received first immunizations C) An adolescent who had a basketball physical D) A middle-aged adult with joint pain and stiffness
When a grieving person is unaware of the connection between physical symptoms or maladaptive behaviors and the grief or loss, that grief is said to be ____________________
Fill in the blank(s) with correct word