Trisomy 13, trisomy 18, and trisomy 21 have which in common?
a. Viability is rare.
b. They are considered deletion syndromes.
c. Diagnosis is difficult, time-consuming, and expensive.
d. Diagnosis can be made early, based on physical characteristics.
ANS: D
Each of these disorders, trisomy 13, 18, and 21, has unique physical characteristics. A presumptive diagnosis can often be made soon after birth and later confirmed by chromosomal analysis. Children with trisomy 13 and 18 usually have short life expectancies. Trisomy 21 has a variable life expectancy, with 80% of individuals living to age 30 years. Trisomy 13, trisomy 18, and trisomy 21 are not deletion syndromes.
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