Discuss why splenectomy is a viable treatment for chronic autoimmune diseases targeted at circulating neutrophils

What will be an ideal response?


Neutrophils targeted by autoantibodies are predominantly destroyed in the spleen through uptake by splenic macrophages via Fc receptors and the complement receptor CR1. Splenectomy would thus reduce the rate at which neutrophils are destroyed. By themselves, antibodies and complement bound to the neutrophil surface do not impair the normal function of neutrophils. In addition, white blood cells are far less susceptible to the formation of membrane-attack complement complexes, owing to the continual production of complement regulatory proteins in these nucleated cells.

Health & Biomechanics

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Benzodiazepine drugs are used to treat anxiety but also have a hypnotic effect to treat insomnia because they enhance the action of the neurotransmitter ________

A) dopamine B) acetylcholine C) epinephrine D) GABA

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K+

Write the medical term for the abbreviation stands.

Health & Biomechanics

Upon sexual stimulation, nipple and clitoral erection occur in response to

A. vasocongestion. B. extracellular fluid buildup. C. muscle tension. D. inflammation.

Health & Biomechanics

What is the best way to judge the intensity of your workout?

A. heavy breathing B. heavy sweating C. using a fitness wristband D. using the Talk Test E. a pedometer reading

Health & Biomechanics