The nurse instructs a patient about doxazosin (Cardura). Which statement by the patient to the nurse indicates understanding about the instructions?
A. "It is common to have nightmares and insomnia."
B. "I need to take the medication on an empty stomach."
C. "The medication should be taken tonight before I go to bed."
D. "I should stop taking the medication if I feel lightheaded."
Ans: C. "The medication should be taken tonight before I go to bed."
Rationale: Doxazosin (Cardura) is a selective, competitive inhibitor of alpha1-adrenergic receptors and is indicated for hypertension. The first dose can cause profound hypotension, which can be minimized by giving the initial dose at bedtime. Doxazosin may be given with or without food. Doxazosin may cause orthostatic hypotension; patients may experience lightheadedness and dizziness. Propranolol (a beta blocker) may cause nightmares and insomnia.
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