The nurse in the emergency department frequently sees clients who have overdosed on acetaminophen (Tylenol). Which client is at highest risk for developing hemolysis?
1. A Native American client
2. A Jewish client
3. An African American client
4. A Caucasian client
3
Rationale 1: Native Americans are not known to have a G6PD enzyme deficiency so they are not at risk for developing hemolysis after ingestion of acetaminophen (Tylenol).
Rationale 2: Jewish clients are not known to have a G6PD enzyme deficiency so they are not at risk for developing hemolysis after ingestion of acetaminophen (Tylenol).
Rationale 3: African Americans have higher rates of G6PD enzyme deficiency. Clients with this deficiency are at risk for developing hemolysis after ingestion of certain drugs, including acetaminophen (Tylenol).
Rationale 4: Caucasians are not known to have a G6PD enzyme deficiency so they are not at risk for developing hemolysis after ingestion of acetaminophen (Tylenol).
Global Rationale: African Americans have higher rates of G6PD enzyme deficiency. Clients with this deficiency are at risk for developing hemolysis after ingestion of certain drugs, including acetaminophen (Tylenol). Native Americans, Jewish clients, and Caucasians are not known to have a G6PD enzyme deficiency so they are not at risk for developing hemolysis after ingestion of acetaminophen (Tylenol).
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