Which of the following is NOT recommended in children with cystic fibrosis?
a. Systemic corticosteroids
b. High-dose ibuprofen
c. Inhaled antibiotics
d. Inhaled DNase (Dornase alpha) (Pulmozyme®)
A
Systemic glucocorticoids are not recommended in children and adolescents with CF. The benefits of systemic glucocorticoids are outweighed by the adverse effects on growth retardation, glucose metabolism, development of CF-related diabetes, and cataract risks. High-dose ibuprofen is recommended in children and young adolescents with mild CF. Ibuprofen has been shown to reduce bronchial inflammation without hindering bacterial clearance. Antibiotics are commonly administered to prevent or combat chronic respiratory tract infections. Inhaled DNase (Dornase alpha) (Pulmozyme®) has been shown to be especially helpful in the management of patients with moderate to severe CF. This aerosolized agent is an enzyme that breaks down the DNA of the thick bronchial mucus associated with chronic bacterial infections with CF.
You might also like to view...
Part of the immune system, a clear fluid containing proteins, salts, organic substances, and water:
A) bile. B) blood. C) lymph. D) tears.
Pediatric patients are ________ likely to become hypovolemic from head injuries than adult patients
A) more B) less C) equally D) Pediatric patients always become hypovolemic due to the movable fontanels.
Answer the following statement(s) true (T) or false (F)
1. The abdominal cavity is divided into four regions. 2. A basic understanding of chemistry is needed when studying the anatomy and physiology of the body because of all the medications and environmental chemicals used. 3. Chemistry is the study of the composition of matter and how matter changes. 4. A molecule is formed when two compounds combine. 5. Water is an atom.
All of the following represent a complete AC electrical circuit EXCEPT:
a. C battery ? C battery ? wire ? flashlight bulb b. ESU generator ? bipolar cord ? one prong of bipolar forceps ? tissue ? other prong of bipolar forceps ? bipolar cord ? ESU generator c. positive (hot) wire ? negative (neutral) wire ? ground source d. wall plug ? ESU generator ? active electrode pencil ? tissues ? patient ground pad ? ESU generator ? wall plug