Which correctly describes the cause of the increase in alveolar ventilation that occurs when a person ascends to high altitude?

A. The decrease in PCO2 of inspired air decreases alveolar PCO2, stimulating the central chemoreceptors.
B. The decrease in total atmospheric pressure causes a greater negative pressure in the intrapleural space, resulting in deeper and more frequent breathing. 
C. The decrease in PCO2 of inspired air decreases alveolar PCO2, stimulating the peripheral chemoreceptors.
D. The decrease in PO2 of inspired air decreases alveolar and arterial PO2, stimulating the peripheral chemoreceptors.
E. The decrease in the total barometric pressure at high altitude causes hypocapnea, which stimulates peripheral chemoreceptors.


Answer: D

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