PD-1 is a negative co-stimulatory signal expressed by tumor cells. What advantage would the expression of PD-1 have in a tumor cell avoiding the immune response?
A. None. Tumor cells are recognized as self and therefore do not pose a health threat.
B. Tumor cells can avoid being killed by activated TC cells.
C. Tumor cells can avoid apoptosis triggered by TH cells.
D. Tumor cells avoid phagocytosis by dendritic cells.
E. Tumor cells are stimulated to reproduce much faster than tumor cells that do not express PD-1.
B
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