In the early 1800s, it became clear that the standardization of drug purity and strength was necessary. Which reasons reflected this need?
1. Strength and purity of products varied from region to region and batch to batch.
2. Strength and purity of products depended on the pharmacist's experience.
3. Strength and purity of products would vary in size, taste, and nutritional value.
4. Strength and purity were mostly guaranteed if products were produced locally, which caused a hardship for those outside the region.
5. Strength and purity could be trusted when the product had gone through extensive local testing.
Correct Answer: 1,2,3
Rationale 1: The strength and purity of the products varied considerably because they were dependent on the experience of the pharmacist and the quality of the local ingredients, which could vary from region to region and batch to batch.
Rationale 2: The strength and purity of the products varied considerably because they were dependent on the experience of the pharmacist and the quality of the local ingredients, which could vary from region to region and batch to batch.
Rationale 3: The strength and purity of the products varied considerably because they were dependent on the experience of the pharmacist and the quality of the local ingredients, which could vary from region to region and batch to batch.
Rationale 4: Strength and purity could not be guaranteed, even if produced locally. Causing a hardship on those outside the region had nothing to do with determining that standardization was needed.
Rationale 5: Extensive testing prior to marketing did not occur until the early 1930s.
Global Rationale: The strength and purity of the products varied considerably because they were dependent on the experience of the pharmacist and the quality of the local ingredients, which could vary from region to region and batch to batch. Because of this, standardization was necessary. Strength and purity could not be guaranteed, even if produced locally. Causing a hardship on those outside the region had nothing to do with determining that standardization was needed. Extensive testing prior to marketing did not occur until the early 1930s.
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