The nursing instructor is explaining the drug lidocaine (Xylocaine) to nursing students who are about to enter their surgical rotation. Which information should be included?

Question

Standard Text: Select all that apply.
1. Amides block sodium from entering the cell.
2. Lidocaine has a longer duration of action than many of the esters.
3. Amides have fewer side effects than do esters.
4. Lidocaine is a calcium blocker.
5. Lidocaine and cocaine are from the same drug class.

Answer 1

Correct Answer: 1,2,3
Rationale 1: Amides decrease the sodium flux into the neuron, thus inhibiting the initial depolarization and conduction of the nerve impulse.
Rationale 2: Lidocaine is an amide-type local anesthetic, which has a longer duration of action than esters.
Rationale 3: Amides such as lidocaine have largely replaced the administration of agents from the ester class, because they produce fewer side effects.
Rationale 4: Amides such as lidocaine block sodium from entering the cell.
Rationale 5: Cocaine is a natural ester, while lidocaine is an amide.
Global Rationale: Amides decrease the sodium flux into the neuron, thus inhibiting the initial depolarization and conduction of the nerve impulse. Lidocaine is an amide-type local anesthetic, which has a longer duration of action than esters. Amides such as lidocaine have largely replaced the administration of agents from the ester class, because they produce fewer side effects. Amides such as lidocaine block sodium from entering the cell. Cocaine is a natural ester, while lidocaine is an amide.