For each description of a molecule involved in lymphocyte migration in questions 8-12, choose the lettered description (A-I) that most closely matches it.This molecule is expressed on activated endothelium, is a member of the immunoglobulin superfamily, a

A. Peripheral lymph node addressin
B. Intercellular adhesion molecule-1 (ICAM-1)
C. Very late activation antigen-4 (VLA-4)
D. E-selectin
E. P-selectin ligand
F. CCR7
G. CXCR5
H. MadCAM-1
I. Vascular cell adhesion molecule-1 (VCAM-1)

This molecule is expressed on activated endothelium, is a member of the immunoglobulin superfamily, and binds to ?1 integrins on activated T cells.


ANS: B.  Intercellular adhesion molecule-1 (ICAM-1) on endothelial cells binds to the integrin LFA-1 on activated T cells.

Health & Biomechanics

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Answer the following statement true (T) or false (F)

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