A patient with a decreased T4 level but an elevated TSH level has
a. primary Cushing syndrome. c. thyrotoxicosis.
b. Addison disease. d. myxedema.
D
Myxedema is hypothyroidism and is indicated by a high thyroid-stimulating hormone (TSH) and low serum T4 levels. Thyrotoxicosis is hyperthyroidism and is indicated by very low TSH, high serum T4, and increased T3:T4 ratio. Addison disease is a rare disorder of the adrenal cortex that involves hyposecretion of glucocorticoids (cortisol), sometimes occurring with hyposecretion of mineralocorticoids (aldosterone). Cushing syndrome is caused by the excess release of the glucocorticoid hormone cortisol.
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