Low leptin levels have been observed in athletes with chronic negative energy balance. What might be a possible explanation for this? Would you expect neuropeptide Y (NPY) levels to be high? Explain.

What will be an ideal response?


Leptin is believed to provide negative feedback to the hypothalamus and result in decreased food intake. Therefore,
in a state where food intake is too low, it would make sense that leptin levels would be low. NPY, however, appears
to be a stimulus for food intake. Therefore, in these athletes, we would expect NPY to be high.

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