Briefly describe the steps in bone resorption
What will be an ideal response
during bone resorption, an osteoclast attaches tightly to the endosteum or periosteum of the bone and forms a leak proof seal at the edges. Then it releases protein-digesting lysosomal enzymes and several amino acids into the sealed pocket. The enzymes digest collagen fibers and other organic substances while the acids dissolve the bone materials. Working together several osteoclasts carve out a small tunnel in the old bone. The degraded bone proteins and extracellular matrix minerals enter an osteoclast by endocytosis, cross the cell in vesicles, and undergo exocytosis on the side opposite the ruffled border. Now in the interstitial fluid, the products of bone resorption diffuse into nearby blood capillaries. Once a small area of bone has been resorbed, osteoclasts depart and osteoblasts move in to rebuild bone in that area.
Question type: Multiple Choice
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