Which analysis of maternal serum may predict chromosomal abnormalities in the fetus?
a. Multiple-marker screening
b. Lecithin-sphingomyelin ratio
c. Biophysical profile
d. Blood type and crossmatch of maternal and fetal serum
A
Maternal serum can be analyzed for abnormal levels of alpha-fetoprotein (AFP), human chorionic gonadotropin, inhibin A, and estriol. The multiple-marker screening may predict chromosomal defects in the fetus. The lecithin-sphingomyelin ratio is used to determine fetal lung maturity. Biophysical profile is used to evaluate fetal status during the antepartum period. Five variables are used, but none are concerned with chromosomal problems. The blood type and crossmatch will not predict chromosomal defects in the fetus.
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